School of Medicine - Medicine

  • Professor
  • LEE, SOO YOUN
  • +82-2-3410-1834

Journal Articles

  • (2024)  Serum trace elements during treatment in pancreatic cancer patients and their associations with cancer prognosis.  CLINICAL NUTRITION.  43,  .
  • (2024)  Therapeutic Drug Monitoring of 6 New-Generation Antiseizure Medications Using a Mass Spectrometry Method.  ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE.  .,  .
  • (2023)  Simultaneous Measurement and Distribution Analysis of Urinary Nicotine, Cotinine, Trans-3'-Hydroxycotinine, Nornicotine, Anabasine, and Total Nicotine Equivalents in a Large Korean Population.  MOLECULES.  28,  23
  • (2023)  Analysis of MicroRNA Signature Differentially Expressed in Pancreatic Islet Cells Treated with Pancreatic Cancer-Derived Exosomes.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  24,  18
  • (2023)  Comprehensive Evaluation of the NeoBase 2 Non-derivatized MSMS Assay and Exploration of Analytes With Significantly Different Concentrations Between Term and Preterm Neonates.  ANNALS OF LABORATORY MEDICINE.  43,  5
  • (2023)  Optimal Use and Need for Therapeutic Drug Monitoring of Teicoplanin in Children: A Systematic Review.  JOURNAL OF KOREAN MEDICAL SCIENCE.  38,  7
  • (2022)  A novel splicing variant in GALNS in mucopolysaccharidosis IVA and the necessity of re-evaluating primer sequences.  ANNALS OF HUMAN GENETICS.  86,  6
  • (2022)  NUDT15 intermediate metabolisers are associated with lower loss of response in paediatric Crohn's disease patients treated by combination treatment with infliximab and azathioprine.  ALIMENTARY PHARMACOLOGY & THERAPEUTICS.  55,  8
  • (2022)  A Simple and High-throughput LC-MS/MS Method for Simultaneous Measurement of Nicotine, Cotinine, 3-OH cotinine, Nornicotine, and Anabasine in Urine and its Application in the General Korean Population.  JOURNAL OF ANALYTICAL TOXICOLOGY.  .,  .
  • (2021)  Diagnostic value of multiple serum biomarkers for vancomycin-induced kidney injury.  JOURNAL OF CLINICAL MEDICINE.  10,  21
  • (2021)  Potential role of CMPK1, SLC29A1, and TLE4 polymorphisms in gemcitabine-based chemotherapy in HER2-negative metastatic breast cancer patients: pharmacogenetic study results from the prospective randomized phase II study of eribulin plus gemcitabine versus paclitaxel plus gemcitabine (KCSG-BR-13-11).  ESMO OPEN.  6,  5
  • (2021)  An updated comprehensive review on vitamin a and carotenoids in breast cancer: Mechanisms, genetics, assessment, current evidence, and future clinical implications.  NUTRIENTS.  13,  9
  • (2021)  Levetiracetam therapeutic drug monitoring in a large cohort of korean epileptic patients.  PHARMACEUTICALS.  14,  8
  • (2021)  Proteomic Analysis of the Meniscus Cartilage in Osteoarthritis.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  22,  15
  • (2021)  Application of an LC-MS/MS Method for the Simultaneous Quantification of Homovanillic Acid and Vanillylmandelic Acid for the Diagnosis and Follow-Up of Neuroblastoma in 357 Patients.  MOLECULES.  26,  11
  • (2021)  Serum 5-Hydroxyindoleacetic Acid and Ratio of 5-Hydroxyindoleacetic Acid to Serotonin as Metabolomics Indicators for Acute Oxidative Stress and Inflammation in Vancomycin-Associated Acute Kidney Injury.  ANTIOXIDANTS.  10,  6
  • (2021)  Urinary Free Metanephrines for Diagnosis of Pheochromocytoma and Paraganglioma.  ENDOCRINOLOGY AND METABOLISM.  36,  3
  • (2021)  Methotrexate polyglutamate quantification for clinical application in patients with pediatric acute lymphoblastic leukemia in association with genetic polymorphisms.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.  201,  .
  • (2021)  Effects of Organic Light-Emitting Diodes on Circadian Rhythm and Sleep.  PSYCHIATRY INVESTIGATION.  18,  5
  • (2021)  Multiple-Cycle Polymeric Extracellular Vesicle Precipitation and Its Evaluation by Targeted Mass Spectrometry.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  22,  9

Publications

  • (2023)  Clinical Applications of Mass Spectrometry in Drug Analysis - Part of the Methods in Molecular Biology book series (MIMB,volume 2737).  Springer.  Lead author
  • (2016)  임상약물유전학 검사와 적용.  아이비기획.  Lead author

Patent/Intellectual Property

  • 질량분석기반 정량분석법을 이용한 아밀로이드 단백질의 아형진단방법.  10-2014-0089789.  20170711.  KOREA, REPUBLIC OF
  • 햅토글로빈의 질량분석용 조성물 및 이를 이용하여 암을 진단하는 방법.  10-2011-0080318.  20141124.  KOREA, REPUBLIC OF
  • 카텝신 D와 매트릭스 메탈로프로틴나제-7의 측정수단을 포함하는 췌장암 진단용 키트..  10-2011-0098548.  20140127.  KOREA, REPUBLIC OF

Conference Paper

  • (2020)  Pharmacokinetic-guided individualized dosing with trough concnetration in vancomycin: Is it outdated and ineffective?.  72nd AACC Annual Meeting.  UNITED STATES
  • (2020)  Comparison of Trough- and Area Under Curve-based Therapeutic Drug Monitoring of Vancomycin.  KSLM.  KOREA, REPUBLIC OF
  • (2020)  Development and Validation of a Simple and Fast LC-MS/MS method for Simultaneous Determination of 6 New Antiepileptic Drugs using Liquid Chromatography-Tandem Mass Spectrometry.  LMCE 2020.  KOREA, REPUBLIC OF
  • (2020)  LC-MS/MS method for simultaneous quantitation of urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) and comparison of random vs. 24 hour urine specimens for diagnosis of neuroblastoma.  LMCE 2020.  KOREA, REPUBLIC OF
  • (2020)  Levetiracetam Therapeutic Drug Monitoring in 550 Korean Patients with Epilepsy.  LMCE 2020.  KOREA, REPUBLIC OF
  • (2020)  Therapeutic Drug Monitoring.  KSLM.  KOREA, REPUBLIC OF
  • (2019)  A large-scale evaluation of therapeutic drug monitoring and pharmacokinetic consultation service for vancomycin treatment.  LMCE 2019.  KOREA, REPUBLIC OF
  • (2019)  Simple and High-throughput LC-MS/MS Method for Simultaneous Measurement of Five Smoking-Related Metabolites in Urine.  MSACL EU.  AUSTRIA
  • (2019)  Clinical application of a simple and reliable LC-MS/MS method for Teicoplanin Drug Monitoring : 3 Year Experience at a Teaching University Hospital.  AACC.  UNITED STATES
  • (2019)  Development and validation of a LC-MS/MS for simultaneous quantification of salivary melatonin and cortisol.  AACC.  UNITED STATES
  • (2019)  Development and Validation of a Novel Warfarin Dosing Algorithm for Korean patients with VKORC1 1173C.  대한진단유전학회 학술대회.  KOREA, REPUBLIC OF
  • (2019)  Impact of various genetic polymorphisms in thiopurine treatment-associated outcomes in Korean patients with Crohn's disease.  대한진단유전학회 학술대회.  KOREA, REPUBLIC OF
  • (2019)  Experience with therapeutic drug monitoring of three antifungal agents using LC-MS/MS method in routine clinical practice.  IFCC-EFLM EurMedLab.  SPAIN
  • (2018)  Cliical pharmacogenomic testing.  IJCGM 2018.  KOREA, REPUBLIC OF
  • (2018)  Biochemical and moleular genetic characteristics in Korean patients with 17-a-hydroxylase/17,20-lyase deficiency.  LMCE 2018 meeting.  KOREA, REPUBLIC OF
  • (2018)  Current status of clinical mass spectrometry in Korea.  LMCE 2018 meeting.  KOREA, REPUBLIC OF
  • (2017)  국내 임상검사실의 질량분석법 이용 현황과 연구위원회 소개.  대한임상화학회 2017년 추계학술대회 초록집.  KOREA, REPUBLIC OF
  • (2017)  국내임상검사실 질량분석이용현황.  대한임상화학회 추계학회 초록집.  KOREA, REPUBLIC OF
  • (2017)  Thoipurine metabolite monitoring.  2017년도 대한임상약리학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2017)  Therapeutic drug monitoring.  대한임상화학검사학회 추계학술대회.  KOREA, REPUBLIC OF

Activities

  • (2010)  Diagnostic Usefulness of Serum Cathepsin D, Tissue Inhibitors of Metalloproteinases and Insulin-Like Growth Factor Binding Proteins for Pancreatic Ductal Adenocarcinoma.  KOREA, REPUBLIC OF, 
  • (2010)  Association of genetic polymorphisms on therapeutic response in pancreatic cancer patients treated with gemcitabine.  KOREA, REPUBLIC OF, 
  • (2010)  Therapeutic Drug Monitoring Experience of Oxcarbazepine in Epileptic patients in a Natural clinical Setting.  KOREA, REPUBLIC OF, 
  • (2010)  Therapeutic drug monitoring experience of oxcarbazepine with epileptic patients in a natural clinical setting.  UNITED STATES, 
  • (2010)  Urinary stone risk profile in the korean patients with urolithiasis.  UNITED STATES, 
  • (2010)  Correlation of genetic polymorphisms in folate metabolic pathway genes with clinical outcomes in pemetrexed-treated advanced NSCLS patients..  UNITED STATES, 
  • (2010)  Genetic polymorphism associated with chronic neurotoxicity and recurrence in curatively-resected colon cancer patients receiving oxaliplatin-based adjuvant chemotherapy.  UNITED STATES, 
  • (2010)  Association of genetic variation in tamoxifen-metabolizing enzymes and plasma concentration of tamoxifen metabolties.  UNITED STATES, 
  • (2008)  HLA CLASS I POLYMORPHISMS OF KOREAN HAVING DISCREPANCIES BETWEEN GENERIC AND ALLELIC TYPES IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION PATIENTS.  CANADA, 
  • (2008)  Microarray analysis of tumor gene expression alterations elicited by celecoxib pretreatment in colorectal adenocarcinoma patients..  UNITED STATES, 
  • (2005)  Allele Frequencies fo DPYD and TYMS Gene in the Korean Population.  KOREA, REPUBLIC OF, 
  • (2005)  Determination of Iohexol Clearance by High-Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS).  NETHERLANDS, 
  • (2005)  Pharmacokinetic study of Orphenadrine using High-Performance Liquid Chromatography-Tandem Mass Spectrometry(HPLC-MS/MS).  NETHERLANDS, 
  • (2004)  Immunosupressive drug monitoring (심포지움 강의).  KOREA, REPUBLIC OF, 
  • (2004)  5-FU 독성증상을 보인 3명의 고형암 환자와 10명 정상인의 DPD 유전형 분석(포스터).  KOREA, REPUBLIC OF, 
  • (2004)  A case with decreased CYP2D6 activity presented with unusual response to nortriptyline medication(포스터).  KOREA, REPUBLIC OF, 
  • (2004)  CYP2D6 genotype distribution and its impact on nortriptyline metabolism in Korean population. (포스터).  KOREA, REPUBLIC OF, 
  • (2004)  Frequency of NAT1 polymorphism in Korean population. (포스터).  KOREA, REPUBLIC OF, 
  • (2004)  GSTM1,T1,P1 Polymorphism in Korean Population(포스터).  KOREA, REPUBLIC OF, 
  • (2004)  Late-onset citrullinemia I presenting a status epilepticus(포스터).  KOREA, REPUBLIC OF,